Achados clínicos-citológicos de patologias bucais em línguas de pacientes com Síndrome de Down

Resumo (EN)

Down syndrome from chromossome 21 s y of human karyotype, leading to mouth disfunctions which could damage teeth, gums, mucosa and gingiva, to name a few. This study assessed both clinically and cytologically several pac1ents· tongues all DS diagnosed co-relating them with possible modifying factors which may interfere in this site, such as gender, age, race, drugs for general use, general and oral alterations, cytological and macroscopic changes of the tongues, plaque index, salivary flow, buffer capacity, presence or absence of xerostomia, and daily food habits. Out of 52 individuals assessed, 38,5% had candidiasis, of which 100% presented xerostomia. Out of those who had candidiasis, 55% had fissured tongue; 13,5% angular cheilitis; 7,7% absent papils; 5,8% blocking of the salivary glands on the lip; 1,9% lip hemangioma and 1,9% geographic tongue. Also, out of the 52 individuals, 23, 1 % presented hypothyroidism, of which 25% had candidiasis. Those who did not have candidiasis (68,8%), were Leukodermas, while others who had it, were melanodermas, and, statistically, there were associations between candidiasis and race (P = O, 041 ). The ones who had candidiasis (40%), presented a SF lower or equivalent to 0,8ml, 30% from 0,8ml to 1,2 mi/minute, 25% from 1,2 to 1,7ml, and only 5% went over 1,7ml. Regarding buffer capacity, 90,4% of the total sample showed a reduced SF presenting salivary PH average of 5,8 and standard deviation of 1.09. The study concludes that individuals DS diagnosed had predisposition to candidiasis, led by important additional modifying factors such as their own anatomical and physiological changes of the tongue, these being inherent characteristics of the syndrome.