Resumo (EN)
Leigh Syndrome (SL) is a neurodegenerative disorder secondary to enzyme deficiencies, including changes in oxidative phosphorylation (OXPHOS) resulting in cognitive and motor function in young children. The diagnosis is by laboratory facilities, high incidence of lactic and pyruvic acid. Besides imaging findings of focal lesions as bilateral basal ganglia and/or brain stem. This article was aimed at describing the clinical case of a child with SL and its response to physiotherapy treatment. The physical therapy, was initiated at two months of life. Ducts physiotherapy were taken once a day (Monday to Friday), with sessions ranging from thirty to forty-five minutes. The treatment period was four years and four months, aimed at maintaining quality of life and prevention of musculoskeletal deformities. After four years and four months of treatment, the patient RNS presented some spontaneous movements such as flexion and extension of upper and lower limbs. It is concluded that physical therapy showed improvements in the movement of upper and lower limbs on the respiratory function of children, particularly as preventive motor pattern.