Resumo (EN)
Objective – To evaluate the anxiety behavior of the zebrafish exposed to two benzodiazepines drugs Clonazepam and Alprazolam. Methods – Fifteen specimens were used on the anxiety tests, six were exposed to Clonazepan and nine to Alprazolam. Animals were exposed in a recipient with 2mg/L of respective drug and, right after, they were moved to the aquarium with the light/dark division. It was counted the permanence time in each portion of the aquarium, quantity of moves and rises to surface. Every subject was observed and the behavior was recorded on video for further analysis. Results – For Clonazepam, even though the individuals stayed more time in the dark side, after the exposition, it was verified a higher number of moves to the white portion. On the other hand, in regarding to Alprazolam, the fishes remained more time in the white portion and there was a higher number of moves to the dark part. Conclusion – Partially, the results demonstrated that drugs can assist on the anxiety combat, because these animals have preference for the dark habitat, which is explained by an anti-predatory behavior. When exposed to the anxiolytics drugs, the behavior tends to suffer alterations, and they start to have preference for the lighter flank.