The impact of different implant approaches in overdenture rehabilitated diabetic patients: A two-year follow-up.

Resumo (EN)

Diabetes Mellitus (DM) is identified as an important condition that leads to implant
complications, and the apico-coronal position and the prosthetic abutment seem to interfere with
peri-implant tissue behavior This study aimed at assessing the effect on peri-implant parameters
after implant loading of two different methodologies in type two diabetics patients (T2DM) who
received implant muco-retained overdentures. Twenty-two mandibular edentulous T2DM received
two implants: Test group: prosthetic abutment of a diameter smaller than the platform of the implant
and a morse taper subcrestal implant level; Control group: prosthetic abutment of diameter identical
to the platform and hexagonal external implant placed at crestal bone level. Clinical, inflammatory,
and tomographic evaluations were performed at baseline (after prosthesis installation), and twelve
and twenty-four months after implant loading. Test implants presented inferior probing depth and
clinical attachment level compared to control at baseline and 12 months (p < 0.05). Test implants
presented reduced levels of pro-inflammatory cytokines at 24 months compared to the control
implants (p < 0.05). The control group had more changes in bone parameters from baseline to the
first and second years (p < 0.05). The test group resulted in reduced bone remodeling and better
clinical conditions and positively modulated peri-implant immunoinflammatory molecules. Trial
identification UTN code: U1111-1239-3638.