Avaliação do grau de eficácia e resposta tecidual entre diferentes produtos com ação antimicrobiana utilizados na interface implante e conector protético

Resumo (EN)

The aim of this study was to evaluate the degree of antibacterial efficacy between dental products at the interface between implant / prosthetic connector, and tissue responses to these products in adjacent tissues. PROHEAL®, CLOREXOAL®, CALEN® and HYDROPAST + I® products were used. For in vitro analysis, 96 implants were implanted with an internal hexagon and 96 prosthetic components of the Straight Trunked type, and two strains of bacteria, Escherichia coli and Staphylococcus aureus. In the in vivo study 15 Wistar rats were used where polyethylene tubes containing the tested drugs and glycerin as a control were inserted into the subcutaneous tissue. After 7, 21 and 42 days the animals were sacrificed and samples used for analysis of the tissue responses. All the drugs tested in the in vitro study, showed reduction of bacterial penetration at the implant / connector interface, and the most effective was CLOREXOAL® (Chlorhexidine 2%) where there was no bacterial growth in the period evaluated. All the drugs tested in the in vivo study, showed an inflammatory response in the subcutaneous tissue of the rats, and the results obtained show equivalence among them. It was possible to conclude that there were different responses to the efficacy and tissue response between the products evaluated at the implant / abutment interface, being clear the greater antimicrobial activity of CLOREXOAL® (chlorhexidine 2%) compared to the other products tested.